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pentobarbital will lower the extent or influence of tamoxifen by affecting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep an eye on.pentobarbital will lower the level or outcome of vincristine liposomal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.buprenorphine subdermal implant and pentobarbital the